产品信息

蛋白质全称	YR结构域锌指蛋白4
别名	PFM1, YR domain containing 4, YR domain containing protein 4, YRDM4, YR/SET domain 4
Uniprot ID	Q80V63
免疫原	KLH偶联的小鼠YRDM4/PFM1合成肽
抗体亚型	IgG
预测分子量./观测分子量.	88 kDa / 88 kDa
纯化方式	亲和纯化

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应用

应用	物种	稀释	阳性样品
WB 免疫印迹	大鼠	1: 300-1: 600	睾丸, 胰腺

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背景

The YRDM family members are characterized by the presence of a YR (positive regulatory) domain and multiple zinc finger (ZnFg) domains. The YR domain defines a family of transcription factors involved in cell differentiation and tumorigenesis. YRDM proteins are either epigenetic modifiers in their own right or else they recruit third party chromatin modifiers - e.g. histone deacetylases (HDACs), histone lysine MTases or histone arginine MTases - to regulate cell type-specific gene expression in various tissues (YRDM4 as an HDAC-associated transcriptional repressor that modulates cell cycle progression.

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图像

WB检测YRDM4/PFM1蛋白(货号 YB113340). 样品: 经RIPA裂解液(货号Y2013)处理的蛋白质. 封闭: 封闭: 3%脱脂牛奶(货号YC310012)溶于TBST溶液, 室温孵育1小时. —抗: 1: 600稀释, 4℃ 孵育过夜. 二抗: HRP标记山羊抗兔IgG (H+L) (货号YB23314), 1: 5000稀释, 室温孵育1小时.

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储存

储存条件	在-20℃下储存一年, 避免反复冻融.
储存缓冲液	含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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注意:

1.本产品仅供研究使用.

2.建议用一抗稀释液(Y2036)稀释本产品.